Close-up of a patient 's hands filling out the SAGE test

Improving Disease Detection

Alzheimer’s is more treatable the earlier it’s detected, making the Self-Administered Gerocognitive Exam (SAGE) instrumental. The SAGE, which was developed by Douglas Scharre, MD, here at Ohio State, is now being used by physicians worldwide.

 

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Did you know...

The SAGE has identified patients 6 months earlier than other testing methods?

Older patient with younger caregiver consulting with a doctor

Slowing Early Alzheimer’s

Early Alzheimer’s is characterized by the appearance of specific toxic protein deposits in the brain. We are conducting the VIVA-MIND Phase 2A clinical trial of an oral drug that could be critical to slowing — and even stopping — disease progression.

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Did you know...

Alzheimer’s begins 20 or more years before symptoms develop?

Dr. Bankiewicz examining a vial in his lab

Gene Therapy’s Promise

Gene therapy is designed to correct mutations in a person’s DNA. At Ohio State’s Gene Therapy Institute, we are pioneering research of the AAV2-BDNF, a study drug administered directly to the brain via surgery. A first-in-human clinical trial is now underway that could hold promise for future Alzheimer’s treatment.

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Did you know...

Ohio State has conducted 200 dementia-related clinical trials over 20 years?

How you can help

Donate by Mail

The Wexner Medical Center Development Office
c/o The OSU Foundation 
PO Box 710811
Columbus, OH 43271-0811

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