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Center for Microbial Interface Biology (CMIB)   

Balagopal A, MacFarlane AS, Mohapatra N, Soni S, Gunn JS, Schlesinger LS. Characterization of the receptor-ligand pathways important for entry and survival of Francisella novicida and the live vaccine strain (LVS) of F. tularensis in human macrophages. Infection and Immunity 2006;74:5114-5125.

Ben Nasr A, Haithcoat J, Masterson JE, Gunn JS, Eaves-Pyles T, Klimpel GR. Critical role for serum opsonins and complement receptors CR3 (CD11b/CD18) and CR4 (CD11c/CD18) in phagocytosis of Francisella tularensis by human dendritic cells (DC): uptake of francisella leads to activation of immature DCs and intracellular survival of the bacteria. Journal of Leukocyte Biology 2006;80:774-86.

Crowther JE, Schlesinger LS. Defining the phagocytic pathway for Surfactant Protein A in human macrophages: binding, clathrin-dependent Uptake, and trafficking through the endolysosomal pathway. American Journal of Physiology-Lung Cellular and Molecular Physiology 2006;290:L334-L342.

Ferguson JS, Martin JL, Azad AK, McCarthy TR, Kang PB, Voelker DR, Crouch EC, Schlesinger LS. Surfactant Protein D Increases fusion of Mycobacterium tuberculosis-containing phagosomes with lysosomes in human macrophages.  Infection and Immunity 2006;74:7005-7009.

Flaherty DK, Vesosky B, Beamer GL, Stromberg P, Turner J. Exposure to Mycobacterium avium can modulate established immunity against Mycobacterium tuberculosis infection generated by Mycobacterium bovis BCG vaccination. Journal of Leukocyte Biology 2006;80:262-1271.

Gavrilin MA, Bouakl I, Knatz N, Duncan M, Hall MW, Gunn JS, Wewers MD. Internalization and phagosome escape required for live Francisella to induce human monocyte IL-1β processing and release. Proceedings of the National Academy of Sciences 2006;103:141-146.

Hall-Stoodley L, Watts G, Crowther JE, Balagopal A, Torrelles JB, Robison-Cox J, Bargatze RF, Harmsen AG, Crouch EC, Schlesinger LS. Mycobacterium tuberculosis binding to human surfactant proteins A and D, Fibronectin and small airway epithelial cells under shear conditions. Infection and Immunity 2006;74:3587-3596. 

Kulkarni MM, McMaster WR, Kamysz E, Kamysz W, Engman DM, McGwire BS. The surface-metalloprotease of the parasitic protozoan, Leishmania, protects against antimicrobial peptide-induced apoptotic killing. Molecular Microbiology 2006;62(5):1484-1497.

Marion CL, Rappleye CA, Engle JT, Goldman WE. An alpha-(1,4)-amylase is essential for alpha-(1,3)-glucan production and virulence in Histoplasma capsulatum. Molecular Microbiology 2006 Nov;62(4):970-83.

Merighi M, Carroll-Portillo AM, Septer AN, Bhatiya A, Gunn JS. The role of Salmonella enterica serovar Typhimurium two-component system PreA-PreB in modulating PmrA-regulated gene transcription. Journal of Bacteriology 2006;188:141-149.

Parsa KVL, Ganesan LP, Rajaram MVS, Gavrilin MA, Balagopal A, Mohapatra NP, Wewers MD, Schlesinger LS, Gunn JS, Tridandapani S. Macrophage pro-inflammatory response to Francisella novicida infection is regulated by the SH2 domain-containing inositol 5’ phosphatase SHIP. PLOS Pathogens 2006;2:0681-0690.

Rajaram MVS, Ganesan LP, Parsa KVL, Butchar JP, Gunn JS, Tridandapani S. Akt/PKB modulates macrophage inflammatory response to Fransicella infection and confers a survival advantage in mice. Journal of Immunology 2006;177:6317-24.

Rappleye CA, Goldman WE.  Defining virulence genes in the dimorphic fungi. Annual Review of Microbiology  2006;60:281-303.

Schlesinger LS. Role of M. tuberculosis cell wall carbohydrates in host adaptation. Glycobiology 2006;16:1111.

Torrelles JB, Azad AK, Schlesinger LS. Fine discrimination in the recognition of individual species of phosphatidyl-myo-inositol mannosides from Mycobacterium tuberculosis by C-type lectin pattern recognition receptors. Journal of Immunology 2006;177:1805-1816.

Vesosky B, Flaherty DK, Turner J. Th1 cytokines facilitate CD8 T cell mediated early resistance to infection with Mycobacterium tuberculosis in old mice. Infection and Immunity 2006;74(6): 3314-3324.

Vesosky B, Flaherty DK, Rottinghaus EK, Beamer GL, Turner J. Age dependent increase in early resistance of mice to Mycobacterium tuberculosis is associated with an increase in CD8 T cells that are capable of antigen independent IFN-g production. Experimental Gerontology 2006;41:1185-1194.