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Research

Ohio State University Medical Center’s Diabetes Research Center is committed to conducting clinical trials and basic research that translate to managing, preventing and curing diabetes. Patients have access to participate in state-of-the-art clinical trials for new drugs and technologies. The DRC has a dedicated clinical trial unit. 

Ohio State’s Diabetes Research Center has initiated novel therapies and strategies to:

  • maintain and sustain the functions of the islet cell transplantation program (ICTP) and pancreas allograft transplantation (PAT)
  • research diabetes and cardiovascular  diseases
  • develop unique approaches for the prevention of type 2 diabetes
  • develop a Community Diabetes Program
  • participate in state-of-the-art and cutting edge clinical trials in diabetes
  • develop new technologies in the management of patients with diabetes.
     

Ohio State's Pioneering Role in Islet Cell Transplantation Program (ICTP)

Research has shown that islet cells can be transplanted into the liver to restore the ability to manufacture the insulin hormone and control glucose, thereby curing a person of diabetes. Ohio State’s DRC successfully received approval from the Food and Drug Administration (FDA) and United Network of Organ Sharing (UNOS) to initiate human islet transplantation at the Medical Center. We have recruited additional faculty for both basic and translational research in Islet Cell Transplantation, which will complement our successful Pancreas Transplantation Program (PAT). 

The objectives of ICTP are to develop new innovative therapies to ensure prolongation and preservation of islet cell function in humans by immunoprotection as well as promote islet cell growth and anti-apoptosis (prevent cell death). Our diverse ICTP team includes clinical and basic scientists, diabetologists, immunologists, transplant surgeons as well as industry partnerships to advance the course of our diabetes program and to expedite the implementation and translation of the research findings to the care of patients with diabetes.

Ohio State Research Programs Include:

  • Islet Cell Transplantation Program
  • Intensive In-hospital Diabetes Management Program
  • Community Diabetes Education  and Outreach Program
  • Non-Human Primate  Islet Cell Transplantation Program
  • Human  Pancreas  and Islet Cell Transplantation Program
  • Pancreas Transplantation Program
  • Ethnicity/Race and  Diabetes
  • Exercise, Diabetes and Cardiovascular Diseases
  • Ethnicity/Race and  Cardiovascular Diseases
  • Obesity, Lipids and Cardiovascular Diseases
  • Insulin Pump
  • Real-time Continuous Glucose Sensor

    Contact Us:
    For more information about clinical trials at Ohio State, please contact:
    Trish Green, RD, CDE
    Research Coordinator
    The Division of Endocrinology, Diabetes and Metabolism
    The Ohio State University
    495 McCampbell Hall
    Phone: (614) 247-7698
    Fax: (614) 292-5417
    patricia.green@osumc.edu

     

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